Product name: Iodixanol

CAS Number：92339-11-2

Molecular Formula：C35H44I6N6O15

Molecular Weight：1550.18

Introduction： Iodixanol is an iodine-containing non-ionic radiocontrast agent.It is sold under the trade name Visipaque; It is also sold as a density gradient medium under the name OptiPrep.Visipaque is commonly used as a contrast agent during coronary angiography. It is the only iso-osmolar contrast agent, with an osmolality of 290 mOsm/kg H2O, the same as blood. It is sold in 2 main concentrations 270 mgI/ml and 320 mgI/ml - hence the name Visipaque 270 or 320. It is sold in single dose units and a large 500 ml plastic bottle for multi-dose dispensing.

  It was originally made by Nycomed, which then merged with Amersham which finally was bought by Jeff Immelt to become GE Healthcare. The majority of Visipaque is made in Cork, Ireland, with additional plants in China and Oslo. All Iodixanol bulk powder is made in Norway by GE Healthcare.

A very similar product also manufactured by GE Healthcare is Omnipaque (Iohexol as the main drug substance).

Iodixanol is also the active ingredient in a number of 'cushion' products used during the centrifugation of stallion semen. It is layered underneath the extended stallion semen allowing for a higher g force to be used with less sperm damage and better recovery rates. Post centrifugation the supernatant above and the cushion below is removed, leaving a concentrated sperm pellet in the conical tube.

CHEMFISH TOKYO CO.,LTD  

Add:1-23-28,Jingumae,shibuya-ku,tokyo, Japan

Email: sales@chemfish.co.jp 

http://www.chemfish.co.jp 

Photoinitiators, Electrolyte Additives, LCD chemicals ,Ionic Liquids ,Intermediates

Customs synthesis --Special reactions:Bromination reaction/ High and low pressure reaction (controllable at -25 ° C - 300 ° C)/ Hydrogenation reaction/Catalytic reaction / Friedel-Crafts Reaction